2. Signaling Pathways
  3. Vitamin D Related/Nuclear Receptor
  4. Androgen Receptor
  5. Androgen Receptor Ligand

Androgen Receptor Ligand

Androgen Receptor Ligands (15):

Cat. No. Product Name Effect Purity
  • HY-176521A
    AR/BRD4 RIPTAC-1 TFA
    		Ligand 99.61%
    AR/BRD4 RIPTAC-1 (Compound II-5) TFA is an orally active Regulatory-inducible proximity-targeting chimera (RIPTAC). AR/BRD4 RIPTAC-1 TFA induces the formation of a stable ternary complex between the androgen receptor (AR) and BRD4, thereby blocking BRD4 function. AR/BRD4 RIPTAC-1 TFA inhibits the growth and proliferation of tumor cells. AR/BRD4 RIPTAC-1 TFA holds promise for use in prostate cancer research.
  • HY-176521
    AR/BRD4 RIPTAC-1
    		Ligand 98.65%
    AR/BRD4 RIPTAC-1 (Compound II-5) is an orally active Regulatory-inducible proximity-targeting chimera (RIPTAC). AR/BRD4 RIPTAC-1 induces the formation of a stable ternary complex between the androgen receptor (AR) and BRD4, thereby blocking BRD4 function. AR/BRD4 RIPTAC-1 inhibits the growth and proliferation of tumor cells. AR/BRD4 RIPTAC-1 holds promise for use in prostate cancer research.
  • HY-B1095
    Chlormadinone acetate
    		Ligand 98.0%
    Chlormadinone acetate is a progestogen with potent progestogenic activity and antiandrogenic effects. Chlormadinone acetate acts on glucocorticoid receptor, progesterone receptor, androgen receptor, and GABAA receptor. Chlormadinone acetate induces endometrial proliferation in estrogen-pretreated rabbits, inhibits testosterone-stimulated growth of the prostate and seminal vesicles in castrated rats, and reduces the thymus and adrenal weights in juvenile rats. Chlormadinone acetate is applicable to research related to diseases such as depression and reproductive metabolic disorders.
  • HY-168299
    AR ligand-30
    		Ligand
    AR ligand-30 is a target protein ligand for PROTAC Bavdegalutamide (HY-138641), which can be used in prostate cancer research.
  • HY-170330
    AR ligand-33
    		Ligand
    AR ligand-33 is the ligand for androgen receptor, that can be used for synthesis of PROTAC AR Degrader-8 (HY-170329) as the target protein ligand.
  • HY-170450
    AR ligand-38
    		Ligand
    AR ligand-38 is the ligand for androgen receptor, that can be used for synthesis of PROTAC AR Degrader-9 (HY-170448).
  • HY-179605
    AR ligand-49
    		Ligand
    AR ligand-49 (Compound 4q) is a dual ligand for the adenosine A2A receptor (A2AAR) and the A3 receptor (A3AR). Its Ki values are 15 and 4.5 nM respectively. AR ligand-49 exhibits reverse agonistic activity at hA2AAR and antagonistic activity at hA3AR. AR ligand-49 can be used for the study of the design and development of adenosine receptor ligands.
  • HY-123579
    Androgen receptor ligand 4
    		Ligand
    Androgen receptor ligand 4 (Compound MDG486) is an androgen receptor ligand with an IC50 of >100 µM. Androgen receptor ligand 4 can be used in the research of adolescent development.
  • HY-P11443
    SRC2-2 peptide
    		Ligand
    SRC2-2 peptide is a a coactivator-derived mimic targeting androgen receptor (AR) ligand. SRC2-2 peptide is promising for research of prostate cancer.
  • HY-171809
    AR ligand 42
    		Ligand
    AR ligand 42 is a androgen receptor ligand. AR ligand 42 can be used to synthesize androgen receptor PROTAC degrader ITRI-90 (HY-171808).
  • HY-173373
    AR ligand-39
    		Ligand
    AR ligand-39, an androgen receptor (AR) ligand, is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). AR ligand-39 can be used for synthesis PROTAC AR Degrader-10 (HY-173372).
  • HY-150878
    AR ligand-4
    		Ligand
    AR ligand-4 is an androgen receptor (AR) ligand, which can be used for the synthesis of PROTACs, such as ARD-1676 (HY-156111).
  • HY-168697
    AR ligand-37
    		Ligand
    AR ligand-37 is a PROTAC target protein ligand that can be used to synthesize BMS-986365 (HY-158101).
  • HY-176129
    AR ligand 41
    		Ligand
    AR ligand 41 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). AR ligand 41 can be used for the synthesis of BWA-6047 (HY-176128).
  • HY-N13475
    (3R,3′R)-Astaxanthin
    		Ligand
    (3R,3′R)-Astaxanthin is an androgen receptor binder. (3R,3′R)-Astaxanthin can be used in the research of prostate cancer.